Most Cited

Below you will find a list of the top ten most cited papers in the British Journal of Pharmacology published in 2014 and 2015 as well as papers published in 2016 attracting early citations. Date of analysis February 2nd 2017

Top Ten Most Cited Published in 2014 or 2015

Experimental design and analysis and their reporting: new guidance for publication in BJP
Michael J Curtis, Richard A Bond, Domenico Spina, Amrita Ahluwalia, Stephen P A Alexander, Mark A Giembycz, Annette Gilchrist, Daniel Hoyer, Paul A Insel, Angelo A Izzo, Andrew J Lawrence, David J MacEwan, Lawrence D F Moon, Sue Wonnacott, Arthur H Weston and John C McGrath

The Concise Guide to PHARMACOLOGY 2015/16: Enzymes
Stephen PH Alexander, Doriano Fabbro, Eamonn Kelly, Neil Marrion, John A Peters, Helen E Benson, Elena Faccenda, Adam J Pawson, Joanna L Sharman, Christopher Southan, Jamie A Davies and CGTP Collaborators

Implementing guidelines on reporting research using animals (ARRIVE etc.): new requirements for publication in BJP
John C McGrath and Elliot Lilley

The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors
Bubici, Concetta; Papa, Salvatore

The hypocretins/orexins: integrators of multiple physiological functions
Stephen PH Alexander, Anthony P Davenport, Eamonn Kelly, Neil Marrion, John A Peters, Helen E Benson, Elena Faccenda, Adam J Pawson, Joanna L Sharman, Christopher Southan, Jamie A Davies and CGTP Collaborators

JNK signalling in cancer: in need of new, smarter therapeutic targets
Concetta Bubici and Salvatore Papa

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part I. Biochemical and physiological mechanisms
Szabo, Csaba; Ransy, Celine; Modis, Katalin; Andriamihaja, Mireille; Murghes, Baptiste; Coletta, Ciro; Olah, Gabor; Yanagi, Kazunori; Bouillaud, Frederic

First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics
Hazel H Szeto

Transient receptor potential (TRP) channels: a clinical perspective
Yosuke Kaneko and Arpad Szallasi

Parthanatos: mitochondrial-linked mechanisms and therapeutic opportunities
Amos A Fatokun, Valina L Dawson and Ted M Dawson

Lysophospholipid receptor nomenclature review: IUPHAR Review 8
Yasuyuki Kihara, Michael Maceyka, Sarah Spiegel and Jerold Chun

Most Cited Papers Published in 2016 to Date

Microglial M1/M2 polarization and metabolic states
Ruben Orihuela, Christopher A McPherson and Gaylia Jean Harry

Progressive inflammation-mediated neurodegeneration after traumatic brain or spinal cord injury
Alan I Faden, Junfang Wu, Bogdan A Stoica and David J Loane

The contribution of astrocytes and microglia to traumatic brain injury
Ila P Karve, Juliet M Taylor and Peter J Crack

Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt-induced hypertension in mice
S M Krishnan, J K Dowling, Y H Ling, H Diep, C T Chan, D Ferens, M M Kett, A Pinar, C S Samuel, A Vinh, T V Arumugam, T D Hewitson, B K Kemp-Harper, A A B Robertson, M A Cooper, E Latz, A Mansell, C G Sobey and G R Drummond

The anti-inflammatory mediator palmitoylethanolamide enhances the levels of 2-arachidonoyl-glycerol and potentiates its actions at TRPV1 cation channels
Stefania Petrosino, Aniello Schiano Moriello, Santiago Cerrato, Mariella Fusco, Anna Puigdemont, Luciano De Petrocellis and Vincenzo Di Marzo

GPR55 promotes migration and adhesion of colon cancer cells indicating a role in metastasis
J Kargl, L Andersen, C Hasenöhrl, D Feuersinger, A Stančić, A Fauland, C Magnes, A El-Heliebi, S Lax, S Uranitsch, J Haybaeck, A Heinemann and R Schicho

Mirabegron relaxes urethral smooth muscle by a dual mechanism involving β3-adrenoceptor activation and α1-adrenoceptor blockade
E C Alexandre, L R Kiguti, F B Calmasini, F H Silva, K P da Silva, R Ferreira, C A Ribeiro, F Z Mónica, A S Pupo and E Antunes

Pharmacological characterization of the opioid inactive isomers (+)-naltrexone and (+)-naloxone as antagonists of toll-like receptor 4
X Wang, Y Zhang, Y Peng, M R Hutchinson, K C Rice, H Yin and L R Watkins

COPD and squamous cell lung cancer: aberrant inflammation and immunity is the common link
Steven Bozinovski, Ross Vlahos, Desiree Anthony, Jonathan McQualter, Gary Anderson, Louis Irving and Daniel Steinfort

Immunotherapy of cancer: from monoclonal to oligoclonal cocktails of anti-cancer antibodies: IUPHAR Review 18
Silvia Carvalho, Francesca Levi-Schaffer, Michael Sela and Yosef Yarden