Darrell R. Abernethy, MD, PhD
Andrew Lawrence, PhD
This virtual issue of Pharmacology Research & Perspectives is a nice representation of the breadth of outstanding contributions in the area of translational pharmacology that we receive and publish. Studies evaluating potential therapeutic targets including coagulation factor IXa, mitochondrial fission, intestinal immune response and serotonin receptors for obesity demonstrate the broad range of pharmacology we publish. Mechanisms of drug toxicity and their representation as clinical adverse drug effects are the counterpart of drug efficacy, and also areas that are represented. Finally, an important component of clinical translational pharmacology is the determination of drug exposure and optimal drug dose via reporting of pharmacokinetic, pharmacodynamic, and drug interaction studies. The articles in this virtual issue of Pharmacology Research & Perspectives should be of considerable interest to the translational pharmacologist, we believe you will find them of interest and value.